SCHEMBL770810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12881458	0.81	MAPT (0.64)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL772491	0.79	HSD11B1 (0.56)	ALDH1A1HSD11B1NPC1RAB9ATSHR
	SCHEMBL1207237	0.78	MAPT (0.60)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL14017642	0.78	MAPT (0.60)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL6674245	0.78	CHRM1 (0.55)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL6674242	0.78	CHRM1 (0.55)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL6679686	0.78	CHRM1 (0.55)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL770911	0.78	POLB (0.52)	MAPTL3MBTL1THRBATMCHRM1
	SCHEMBL4592901	0.78	MAPT (0.59)	MAPTGAAL3MBTL1THRBATM
	SCHEMBL17690703	0.76	HSD11B1 (0.50)	HSD11B1NPC1RAB9ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.