Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700677 | 0.73 | SYK (0.39) | LSSITGB3ITGA2BSYK | |
| SCHEMBL6513376 | 0.69 | PIM1 (0.43) | SYK | |
| SCHEMBL1674952 | 0.64 | MAPT (0.33) | LSSITGB3ITGA2BSYK | |
| SCHEMBL3166116 | 0.63 | CHKA (0.42) | ITGB3ITGA2B | |
| SCHEMBL7029894 | 0.62 | SYK (0.44) | SYK | |
| SCHEMBL6706219 | 0.61 | PORCN (0.44) | — | |
| SCHEMBL6706218 | 0.61 | PORCN (0.44) | — | |
| SCHEMBL8631656 | 0.60 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL7918841 | 0.60 | SMN1; SMN2 (0.50) | ITGB3ITGA2B | |
| SCHEMBL6703929 | 0.60 | SMN1; SMN2 (0.50) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | Sanofi-Aventis (FR) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006122661-A1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI-AVENTIS (DE) | 2006-11-23 | — | — | WO | disclosed |