SCHEMBL4593813

SCHEMBL4593813

Cc1ccc(C(=O)c2ccccc2)c(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.47
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.44
KDM4E B2RXH2 2/20 0.44
NR4A1 P22736 1/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
KMT2A Q03164 1/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPT P10636 2/20 0.44
MAPK1 P28482 2/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PDK1 Q15118 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK3 Q15120 1/20 0.43
PDK4 Q16654 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5073237 0.88 ALDH1A1 (0.59) AKR1C3ALDH1A1GAAKDM4ENR4A1
SCHEMBL29163182 0.86 MAPK1 (0.53) AKR1C3ALDH1A1GAAKDM4ENR4A1
SCHEMBL28619567 0.85 ALDH1A1 (0.54) AKR1C3ALDH1A1GAANR4A1MAPT
SCHEMBL257374 0.85 AKR1C3 (0.52) AKR1C3ALDH1A1GAAKDM4ENR4A1
SCHEMBL5474049 0.84 AKR1C3 (0.52) AKR1C3ALDH1A1KDM4ENR4A1MEN1
SCHEMBL11498747 0.84 MAPT (0.49) AKR1C3ALDH1A1GAAMEN1USP2
SCHEMBL27573417 0.82 AKR1C3 (0.48) AKR1C3ALDH1A1KDM4ENR4A1MEN1
SCHEMBL2987573 0.81 ALDH1A1 (0.50) AKR1C3ALDH1A1GAAKDM4ENR4A1
SCHEMBL10455760 0.79 LMNA (0.58) AKR1C3ALDH1A1GAAKDM4ENR4A1
SCHEMBL109811 0.78 CLCN2 (0.49) AKR1C3ALDH1A1KDM4ENR4A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1314745-B1 Process for preparing trityl group containing polystyrene resins UNB CHEMICAL CORP (KR) 2008-01-09 EP disclosed
US-6875822-B2 Process for preparing tritylated polystyrene resin BEADTECH, INC. (KR) 2005-04-05 US disclosed
US-20030105243-A1 Process for preparing tritylated polystylene resin UNB CHEMICAL CORPORATION (KR) 2003-06-05 US disclosed
EP-1314745-A1 Process for preparing trityl group containing polystyrene resins Beadtech Inc. (KR) 2003-05-28 EP disclosed