SCHEMBL5073237

SCHEMBL5073237

O=C(c1ccccc1)c1ccc(C(=O)c2ccccc2)c(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
AKR1C3 P42330 1/20 0.58
GAA P10253 2/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
KDM4E B2RXH2 2/20 0.53
USP2 O75604 2/20 0.53
NR4A1 P22736 1/20 0.53
KEAP1 Q14145 1/20 0.53
NFE2L2 Q16236 1/20 0.53
ATM Q13315 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
SRD5A2 P31213 1/20 0.50
HSD17B10 Q99714 3/20 0.49
MAPK1 P28482 2/20 0.49
LMNA P02545 2/20 0.49
PKM P14618 1/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2987573 0.92 ALDH1A1 (0.50) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL10455760 0.90 LMNA (0.58) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL4593813 0.88 AKR1C3 (0.47) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL10455799 0.88 KDM4E (0.49) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL6532690 0.88 NR4A1 (0.49) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL9717032 0.84 AKR1C3 (0.62) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL31380407 0.84 MEN1 (0.49) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL28006231 0.84 AKR1C3 (0.43) ALDH1A1AKR1C3GAAMAPTMEN1
SCHEMBL4595089 0.84 MAPT (0.64) ALDH1A1GAAMAPTKMT2AKDM4E
SCHEMBL30403796 0.83 TSHR (0.64) ALDH1A1AKR1C3GAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0824959-B1 POROUS FILM ASAHI CHEMICAL IND (JP) 2008-01-02 EP disclosed
EP-0796649-B1 PROCESS FOR PREPARING POLYETHER ETHER KETONE MEMBRANE ASAHI CHEMICAL IND (JP) 2006-03-29 EP disclosed
US-6017455-A NON-SULFONATED AROMATIC POLYETHER KETONE COPOLYMER MEMBRANE HAVING CRYSTALLINITY OF 10% BY WEIGHT OR HIGHER AND SPECIFIC PORE DIAMETER; HEAT AND CHEMICAL RESISTANCE; USED TO MAKE ULTRAPURE WATER FOR SEMICONDUCTORS, REMOVAL OF IRON ETC. ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-01-25 US disclosed
US-5997741-A Process for preparing a polyether ether ketone membrane ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1999-12-07 US disclosed
EP-0824959-A1 POROUS FILM Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1998-02-25 EP disclosed
EP-0796649-A1 PROCESS FOR PREPARING POLYETHER ETHER KETONE MEMBRANE Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1997-09-24 EP disclosed
EP-0268112-A2 A novel aromatic polyether and a process for producing a polyether Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-05-25 EP disclosed
EP-0237004-A2 A crystalline aromatic polyketone copolymer and a process for producing the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-09-16 EP disclosed
EP-0210377-A1 Homo- and copolymeric poly(arylenesulfides)containing keto groups, and process for their preparation HÜLS AKTIENGESELLSCHAFT (DE) 1987-02-04 EP disclosed