Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983267 | 0.90 | L3MBTL1 (0.51) | THRATHRBKMT2AL3MBTL1HSD17B3 | |
| SCHEMBL10482996 | 0.84 | HSD17B3 (0.60) | THRATHRBKMT2AL3MBTL1HSD17B3 | |
| SCHEMBL941088 | 0.83 | KMT2A (0.54) | KMT2AL3MBTL1POLBLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL7312871 | 0.81 | KMT2A (0.53) | KMT2AL3MBTL1POLBLMNAKDM4E | |
| SCHEMBL11108445 | 0.80 | KMT2A (0.58) | KMT2AL3MBTL1POLBLMNAKDM4E | |
| SCHEMBL6514676 | 0.80 | HSD17B3 (0.65) | THRATHRBL3MBTL1HSD17B3LMNA | |
| SCHEMBL29081476 | 0.79 | THRA (0.43) | THRATHRBKMT2AL3MBTL1POLB | |
| SCHEMBL29315332 | 0.78 | HSD17B3 (0.53) | THRATHRBL3MBTL1HSD17B3LMNA | |
| SCHEMBL4931177 | 0.78 | CTNNB1 (0.56) | HSD17B3HTR7ALDH1A1MAPTHPGD | |
| SCHEMBL3896481 | 0.78 | OGG1 (0.58) | KMT2AL3MBTL1HSD17B3POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898909-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1898914-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000435-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007000434-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |