SCHEMBL459399

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL459850	0.88	EPHX2 (0.52)	CCR3EPHX2POLB
	SCHEMBL459348	0.85	PARP1 (0.43)	CCR3HRH1EPHX2CCNT1CDK9
	SCHEMBL460042	0.83	KMT2A (0.40)	CCR3HRH1USP2TSHRKMT2A
	SCHEMBL459909	0.82	CCR3 (0.40)	CCR3HRH1OPRM1HPGDS
	SCHEMBL460370	0.81	CCR3 (0.51)	CCR3KMT2AEPHX2
	SCHEMBL459347	0.80	ALDH1A1 (0.45)	CCR3USP2TSHRKMT2AEPHX2
	SCHEMBL459356	0.80	CCR3 (0.53)	CCR3TSHRKMT2AEPHX2
	SCHEMBL460548	0.80	EPHX2 (0.53)	CCR3USP2KMT2AEPHX2ALDH1A1
	SCHEMBL458154	0.80	CCR3 (0.41)	CCR3USP2TSHRKMT2AALDH1A1
	SCHEMBL460097	0.80	DRD2 (0.42)	CCR3USP2TSHRKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.