Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6832895 | 0.90 | ALDH1A1 (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL7701741 | 0.86 | IDH1 (0.35) | CYP3A4LMNAIDH1NPC1RAB9A | |
| SCHEMBL2952892 | 0.85 | ALDH1A1 (0.42) | CYP3A4ALDH1A1CA2LMNAIDH1 | |
| SCHEMBL4594117 | 0.83 | CYP3A4 (0.35) | CYP3A4ALDH1A1CA2LMNAIDH1 | |
| SCHEMBL3830756 | 0.82 | NPC1 (0.45) | CYP3A4ALDH1A1LMNAIDH1NPC1 | |
| SCHEMBL1923120 | 0.81 | NPC1 (0.40) | CYP3A4ALDH1A1LMNAIDH1NPC1 | |
| SCHEMBL20835340 | 0.78 | ALDH1A1 (0.42) | CYP3A4ALDH1A1CA2LMNANPC1 | |
| SCHEMBL77808 | 0.77 | CYP3A4 (0.42) | CYP3A4ALDH1A1CA2LMNATSHR | |
| SCHEMBL8675568 | 0.77 | ALDH1A1 (0.41) | CYP3A4ALDH1A1CA2LMNANPC1 | |
| SCHEMBL13341982 | 0.77 | NPC1 (0.36) | CYP3A4ALDH1A1LMNAIDH1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924644-A1 | POLYURETHANE FLAME RETARDANT COMPOSITIONS | Ciba Holding Inc. (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007031450-A1 | POLYURETHANE FLAME RETARDANT COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-03-22 | — | — | WO | disclosed |