Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834698 | 0.90 | P2RX7 (0.31) | — | |
| SCHEMBL4594115 | 0.86 | CYP3A4 (0.34) | IDH1NPC1RAB9APOLBLMNA | |
| SCHEMBL1923120 | 0.85 | NPC1 (0.40) | IDH1NPC1RAB9AF2RPOLB | |
| SCHEMBL3858691 | 0.83 | ALDH1A1 (0.36) | IDH1NPC1RAB9AF2RLMNA | |
| SCHEMBL30963008 | 0.83 | ALDH1A1 (0.36) | IDH1NPC1RAB9AF2RLMNA | |
| SCHEMBL30963009 | 0.83 | ALDH1A1 (0.36) | IDH1NPC1RAB9AF2RLMNA | |
| SCHEMBL29930396 | 0.83 | ALDH1A1 (0.36) | IDH1NPC1RAB9AF2RLMNA | |
| SCHEMBL3830756 | 0.82 | NPC1 (0.45) | IDH1NPC1RAB9AF2RPOLB | |
| SCHEMBL7701744 | 0.81 | CNR2 (0.38) | NPC1RAB9AF2RPOLBLMNA | |
| SCHEMBL10879715 | 0.80 | NPC1 (0.39) | IDH1NPC1RAB9AF2RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177182-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | Ciba SC Holding AG (CH) | 2002-02-06 | — | — | EP | disclosed |
| EP-1086145-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | Ciba SC Holding AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| WO-2000068218-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-11-16 | — | — | WO | disclosed |
| WO-1999062961-A1 | NOVEL PHOTOINITIATORS AND THEIR APPLICATIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-12-09 | — | — | WO | disclosed |