Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099246 | 1.00 | CTSV (0.52) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL718147 | 0.88 | CTSV (0.52) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL29897031 | 0.88 | CTSV (0.52) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL718146 | 0.88 | CTSV (0.52) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL29896946 | 0.88 | CTSV (0.52) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL2671920 | 0.88 | CTSV (0.52) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL27755531 | 0.86 | CTSV (0.50) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL28809922 | 0.86 | CTSV (0.50) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL10554925 | 0.85 | CTSV (0.54) | CTSVCTSLPOLBFFAR1PIN1 | |
| SCHEMBL27481727 | 0.85 | CTSV (0.54) | CTSVCTSLPOLBFFAR1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7423146-B2 | Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-09 | — | — | US | disclosed |
| EP-1948625-A1 | PROCESS FOR THE PREPARATION OF BETAMIMETIC BENZOXAZINONE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054484-A1 | PROCESS FOR THE PREPARATION OF BETAMIMETIC BENZOXAZINONE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-18 | — | — | WO | disclosed |
| US-20070112191-A1 | Process for the manufacturing of pharmaceutically active compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-17 | — | — | US | disclosed |
| CN-1228448-C | Process for preparing chiral medicine intermediate (R)-2-halogen-1-(substituted phenyl) ethanol | TIANJIN NANKAI GUARD CO LTD (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1554767-A | Process for preparing chiral medicine intermediate (R)-2-halogen-1-(substituted phenyl) ethanol | 天津南开戈德集团有限公司 | 2004-12-15 | — | — | CN | disclosed |
| US-6696573-B1 | SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-12-04 | — | — | US | disclosed |
| CN-1377342-A | Process for preparation of tricyclic amino alcohol derivatives | ASAHI CHEMICAL IND (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1209150-A1 | PROCESSES FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112191-A1 | Process for the manufacturing of pharmaceutically active compounds | FIP1L1, TET2, F3 | CTSV 1523/4885CTSL 218/4885POLB 3475/4885 |
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ADH1A, ADH1C, OXER1 | CTSV 3565/4885CTSL 2274/4885POLB 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.