Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523244 | 0.83 | MAPK14 (0.62) | SMN1; SMN2LMNATP53MAPK14KMT2A | |
| SCHEMBL4378877 | 0.83 | MAPK14 (0.49) | ALDH1A1THRBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4479062 | 0.78 | MAPK14 (0.74) | SMN1; SMN2MAPK14MCHR1 | |
| SCHEMBL461108 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL1240350 | 0.75 | MAPT (0.56) | ALDH1A1MAPTTHRBSMN1; SMN2L3MBTL1 | |
| SCHEMBL460897 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTTHRBSMN1; SMN2LMNA | |
| SCHEMBL4480114 | 0.74 | MAPK14 (0.84) | SMN1; SMN2MAPK14MCHR1 | |
| SCHEMBL21419948 | 0.73 | MAPT (0.56) | MAPTTHRBTP53MAPK14KMT2A | |
| SCHEMBL32665600 | 0.73 | MAPK14 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNATP53 | |
| SCHEMBL29348747 | 0.73 | KMT2A (0.44) | ALDH1A1MAPTTHRBSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |