Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CKS1B | P61024 | 1/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881295 | 0.86 | CYP1A2 (0.54) | ALDH1A1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4462999 | 0.80 | MAPK14 (0.73) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23094452 | 0.79 | MAPK14 (0.52) | ALDH1A1MAPK10HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2946109 | 0.77 | CA1 (0.53) | ALDH1A1TP53CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL459452 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TP53GAASMN1; SMN2MEN1 | |
| SCHEMBL1523244 | 0.76 | MAPK14 (0.62) | TP53SMN1; SMN2ADORA2AMEN1KMT2A | |
| SCHEMBL21575076 | 0.74 | LMNA (0.43) | ALDH1A1MAPK10TP53GAARAB9A | |
| SCHEMBL21634096 | 0.74 | POLB (0.46) | ALDH1A1MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL31066580 | 0.74 | POLB (0.46) | ALDH1A1MAPK10ADORA2AMEN1KMT2A | |
| SCHEMBL2414081 | 0.73 | MAPK10 (0.50) | ALDH1A1MAPK10GAARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |