Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10080764 | 0.87 | MAPT (0.44) | ALDH1A1MAPTTHRBSMN1; SMN2KMT2A | |
| SCHEMBL459562 | 0.85 | POLB (0.47) | ALDH1A1MAPTTHRBSMN1; SMN2LMNA | |
| SCHEMBL459682 | 0.82 | MAPT (0.45) | ALDH1A1MAPTTHRBSMN1; SMN2LMNA | |
| SCHEMBL459616 | 0.81 | MAPT (0.48) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL459452 | 0.74 | ALDH1A1 (0.54) | ALDH1A1MAPTTHRBSMN1; SMN2KMT2A | |
| SCHEMBL460146 | 0.74 | MAPT (0.55) | MAPTKMT2ALMNATP53 | |
| SCHEMBL10080865 | 0.74 | L3MBTL1 (0.56) | EGLN1L3MBTL1 | |
| SCHEMBL9694570 | 0.70 | ADRA1A (0.32) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL1770486 | 0.70 | EGLN1 (0.44) | ALDH1A1MAPTTHRBSMN1; SMN2KMT2A | |
| SCHEMBL1770023 | 0.70 | MAPT (0.56) | ALDH1A1MAPTTHRBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011707-A2 | SUBSTITUTED PYRIDINONE DERIVATIVES AND METHODS FOR MANUFACTURING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2012-01-26 | — | — | WO | disclosed |