Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291274 | 0.79 | MME (0.44) | MMEMAPTCYP1A2CYP2C19ACE | |
| SCHEMBL987319 | 0.79 | MAPK1 (0.52) | MAPK1MMEKDM4EALOX15BCL2 | |
| SCHEMBL988202 | 0.79 | MAPK1 (0.52) | MAPK1MMEKDM4EALOX15BCL2 | |
| SCHEMBL9853724 | 0.77 | MME (0.47) | MMECYP1A2CYP2C19PPM1BSMN1; SMN2 | |
| SCHEMBL16339806 | 0.77 | MME (0.47) | MAPK1MMEKDM4EKMT2AMAPT | |
| SCHEMBL8818604 | 0.76 | CYP2C19 (0.44) | MAPK1MMEKDM4EMEN1KMT2A | |
| SCHEMBL8565353 | 0.74 | MME (0.47) | MMECYP1A2CYP2C19PPM1BSMN1; SMN2 | |
| SCHEMBL9968845 | 0.73 | MME (0.42) | MAPK1MMEKDM4EALOX15BCL2 | |
| SCHEMBL18223738 | 0.72 | ALDH1A1 (0.49) | MAPK1KDM4EALOX15MEN1KMT2A | |
| SCHEMBL4066871 | 0.72 | MAPK1 (0.56) | MAPK1KDM4EALOX15BCL2BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931220-B1 | FLAVOUR MODULATING SUBSTANCES | GIVAUDAN NEDERLAND SERVICES BV (NL) | 2013-05-29 | — | — | EP | disclosed |
| EP-1931220-A1 | FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007040399-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-04-12 | — | — | WO | disclosed |