SCHEMBL9853724 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MME	P08473	1/20	0.47

▸	ALDH1A1	P00352	1/20	0.34

▸	PKM	P14618	1/20	0.34

▸	ACE	P12821	4/20	0.34

▸	CYP2C19	P33261	2/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	PPM1B	O75688	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16339806	0.83	MME (0.47)	MMEALDH1A1PKMCYP2C19CYP1A2
SCHEMBL8565353	0.80	MME (0.47)	MMEALDH1A1PKMCYP2C19CYP1A2
SCHEMBL18137281	0.78	MAPT (0.42)	MMEALDH1A1PKMACESMN1; SMN2
SCHEMBL4594736	0.77	MAPK1 (0.46)	MMEALDH1A1ACECYP2C19CYP1A2
SCHEMBL9291274	0.76	MME (0.44)	MMEACECYP2C19CYP1A2
SCHEMBL8818604	0.76	CYP2C19 (0.44)	MMEALDH1A1CYP2C19CYP1A2PPM1B
SCHEMBL230931	0.75	POLB (0.56)	MMEALDH1A1PKM
SCHEMBL5162325	0.74	ALDH1A1 (0.56)	MMEALDH1A1PKMACECYP2C19
SCHEMBL10703610	0.71	ALDH1A1 (0.36)	MMEALDH1A1PKMACECYP2C19
SCHEMBL4794872	0.70	ALDH1A1 (0.47)	MMEALDH1A1PKMACECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0440298-A1	Topical preparations for treating human nails	BROCADES PHARMA B.V. (NL)	1991-08-07	—	—	EP	disclosed