Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316181 | 0.88 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL27488761 | 0.88 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1169310 | 0.88 | MEN1 (0.50) | MEN1KMT2AAPAF1ACP3SIGMAR1 | |
| SCHEMBL7314848 | 0.88 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8614874 | 0.86 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7315861 | 0.83 | ACP3 (0.47) | MEN1KMT2AAPAF1ACP3SIGMAR1 | |
| SCHEMBL17161710 | 0.81 | MEN1 (0.53) | MEN1KMT2AAPAF1ACP3SIGMAR1 | |
| SCHEMBL10448120 | 0.78 | CYP2C9 (0.44) | MEN1KMT2ASMN1; SMN2ANPEP | |
| SCHEMBL5513822 | 0.76 | ACP3 (0.50) | MEN1KMT2AAPAF1ACP3SIGMAR1 | |
| SCHEMBL7365794 | 0.76 | ACP3 (0.50) | MEN1KMT2AAPAF1ACP3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871379-A2 | CYANOARYLAMINES | Smithkline Beecham Corporation (US) | 2008-01-02 | — | — | EP | claimed |
| WO-2006113552-A2 | CYANOARYLAMINES | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-26 | — | — | WO | claimed |