Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7365794 | 1.00 | ACP3 (0.50) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL5967058 | 0.98 | ACP3 (0.53) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL5967292 | 0.98 | ACP3 (0.53) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL7402142 | 0.85 | ACACB (0.50) | KDM4EALDH1A1LMNAHPGDSIGMAR1 | |
| SCHEMBL7316408 | 0.85 | LMNA (0.50) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL6155794 | 0.84 | APAF1 (0.55) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL6809827 | 0.84 | APAF1 (0.55) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL18722284 | 0.84 | APAF1 (0.55) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL3823989 | 0.84 | APAF1 (0.55) | ACP3KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL2481352 | 0.84 | APAF1 (0.55) | ACP3KDM4EALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799645-A2 | PROCESSES AND INTERMEDIATES FOR PREPARING CYSTEINE PROTEASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006034004-A2 | PROCESSES AND INTERMEDIATES FOR PREPARING CYSTEINE PROTEASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-03-30 | — | — | WO | disclosed |