Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27488761 | 1.00 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAANPEP | |
| SCHEMBL7314848 | 1.00 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2LMNAANPEP | |
| Hydrochloric Acid SCHEMBL8614874 | 0.98 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2LMNAANPEP | |
| SCHEMBL4594817 | 0.88 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2ANPEPPOLB | |
| SCHEMBL7311075 | 0.83 | LMNA (0.47) | KMT2ASMN1; SMN2LMNATRPM8TSHR | |
| SCHEMBL7318693 | 0.83 | LMNA (0.47) | KMT2ASMN1; SMN2LMNATRPM8TSHR | |
| SCHEMBL10448120 | 0.78 | CYP2C9 (0.44) | MEN1KMT2ASMN1; SMN2LMNAANPEP | |
| SCHEMBL7316408 | 0.76 | LMNA (0.50) | KMT2ALMNATRPM8TSHRALDH1A1 | |
| SCHEMBL7284516 | 0.75 | ANPEP (0.53) | MEN1KMT2AANPEPPOLBALDH1A1 | |
| SCHEMBL4179270 | 0.75 | CA2 (0.57) | KMT2ASMN1; SMN2CTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |