Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 2/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17087004 | 0.89 | F2 (0.54) | MAPTGAAGFERKMT2ANPC1 | |
| SCHEMBL17087015 | 0.85 | GPR35 (0.61) | SMN1; SMN2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL17087017 | 0.83 | PTPN1 (0.53) | SMN1; SMN2TP53GAANPC1ALDH1A1 | |
| SCHEMBL1242953 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2TP53TSHREPHX1EPHX2 | |
| SCHEMBL1772808 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2TP53TSHREPHX1EPHX2 | |
| Hydrazine SCHEMBL28432690 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53TSHREPHX1EPHX2 | |
| Benzene SCHEMBL28977956 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53TSHREPHX1EPHX2 | |
| SCHEMBL57554 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53TSHREPHX1EPHX2 | |
| SCHEMBL9011492 | 0.80 | KDM4E (0.58) | SMN1; SMN2TP53TSHREPHX1EPHX2 | |
| SCHEMBL5176164 | 0.80 | KDM1A (0.47) | SMN1; SMN2TP53TSHREPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350334-B2 | Catheter locking solution having antimicrobial and anticoagulation properties | BECTON, DICKINSON AND COMPANY (US) | 2019-07-16 | — | — | US | claimed |
| US-20170368176-A1 | NON-TOXIC TOPICAL ANESTHETIC OPHTHALMIC COMPOSITIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-12-28 | — | — | US | claimed |
| US-20170319757-A1 | Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties | BECTON, DICKINSON AND COMPANY | 2017-11-09 | — | — | US | claimed |
| US-9744273-B2 | Catheter locking solution having antimicrobial and anticoagulation properties | BECTON, DICKSON AND COMPANY (US) | 2017-08-29 | — | — | US | claimed |
| EP-2440261-B1 | A CATHETER LOCKING SOLUTION HAVING ANTIMICROBIAL AND ANTICOAGULATION PROPERTIES | BECTON DICKINSON CO (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2016100209-A1 | NON-TOXIC TOPICAL ANESTHETIC OPHTHALMIC COMPOSITIONS | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2016-06-23 | — | — | WO | claimed |
| US-20160101223-A1 | Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties | BECTON, DICKINSON AND COMPANY | 2016-04-14 | — | — | US | claimed |
| US-9248093-B2 | Catheter locking solution having antimicrobial and anticoagulation properties | BECTON, DICKINSON AND COMPANY (US) | 2016-02-02 | — | — | US | claimed |
| EP-2440261-A2 | A CATHETER LOCKING SOLUTION HAVING ANTIMICROBIAL AND ANTICOAGULATION PROPERTIES | Becton, Dickinson and Company (US) | 2012-04-18 | — | — | EP | claimed |
| US-20100318040-A1 | Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties | BECTON, DICKINSON AND COMPANY (US) | 2010-12-16 | — | — | US | claimed |
| WO-2010144674-A2 | A CATHETER LOCKING SOLUTION HAVING ANTIMICROBIAL AND ANTICOAGULATION PROPERTIES | BECTON, DICKINSON AND COMPANY (US) | 2010-12-16 | — | — | WO | claimed |
| EP-3492075-B1 | NEOSAXITOXIN COMBINATION FORMULATIONS FOR PROLONGED LOCAL ANESTHESIA | CHILDRENS MEDICAL CT CORP (US) | 2023-12-13 | — | — | EP | disclosed |
| US-11834456-B2 | 11,13-modified saxitoxins for the treatment of pain | SITEONE THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| WO-2023211990-A1 | BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230339958-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. | 2023-10-26 | — | — | US | disclosed |
| US-4029794-A | SAXITOXIN | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4022899-A | TETRODOXIN, DESOXYTETRODOXIN, AMINOALKYL BENZOATE | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1977-05-10 | — | — | US | disclosed |
| US-4001413-A | PHARMACEUTICAL LOCAL ANESTHETIC COMPOSITION EMPLOYING SAXITOXIN | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1977-01-04 | — | — | US | disclosed |
| US-3966934-A | AMINOACYL ANILIDE AND A TOXIN | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3957996-A | AMINOACYL ANILIDE, SAXITOXIN, ADMINISTERING | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170319757-A1 | Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties | PROC, PUF60, DEK | SMN1; SMN2 2935/4885TP53 4793/4885TSHR 4167/4885 |
| US-10350334-B2 | Catheter locking solution having antimicrobial and anticoagulation properties | PROC, PUF60, DEK | SMN1; SMN2 2935/4885TP53 4793/4885TSHR 4167/4885 |
| US-11834456-B2 | 11,13-modified saxitoxins for the treatment of pain | SCN11A, SCN10A, CACNA1A | SMN1; SMN2 362/4885TP53 4459/4885TSHR 2253/4885 |
| US-20230339958-A1 | NON-HYDRATED KETONE INHIBITORS OF NAV1.7 FOR THE TREATMENT OF PAIN | SCN7A, SCN10A, HCN3 | SMN1; SMN2 328/4885TP53 4697/4885TSHR 4297/4885 |
| US-20100318040-A1 | Catheter Locking Solution Having Antimicrobial and Anticoagulation Properties | PROC, PUF60, DEK | SMN1; SMN2 2935/4885TP53 4793/4885TSHR 4167/4885 |
| US-20170368176-A1 | NON-TOXIC TOPICAL ANESTHETIC OPHTHALMIC COMPOSITIONS | SCN1B, SCNN1B, CACNB1 | SMN1; SMN2 761/4885TP53 4836/4885TSHR 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.