SCHEMBL4594822

SCHEMBL4594822

CCC(N)Nc1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
CYP1A2 P05177 4/20 0.48
CYP3A4 P08684 3/20 0.48
HSD17B10 Q99714 2/20 0.48
CYP2C19 P33261 2/20 0.48
HIF1A Q16665 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 2/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 3/20 0.44
GAA P10253 3/20 0.44
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
KDM4E B2RXH2 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1072933 0.77 TDP1 (0.50) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL1493202 0.76 CYP1A2 (0.46) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL3999085 0.76 KCNH3 (0.47) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL9359370 0.75 TDP1 (0.54) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL819617 0.74 ALDH1A1 (0.57) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL5377321 0.73 RAB9A (0.50) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL5342232 0.73 RAB9A (0.50) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL5342235 0.73 RAB9A (0.50) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
Hydrochloric Acid SCHEMBL5388102 0.72 RAB9A (0.49) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19
SCHEMBL10401390 0.72 UGT2B7 (0.52) ALDH1A1CYP1A2CYP3A4HSD17B10CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0375503-B1 Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups ELF AQUITAINE (FR) 1996-02-28 EP claimed
EP-0375503-A1 Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups ELF AQUITAINE (FR) 1990-06-27 EP claimed
EP-1355961-B1 ETHYLENE COPOLYMER COMPOSITIONS SUITABLE FOR VISCOSITY INDEX IMPROVERS AND LUBRICANT COMPOSITIONS EXXONMOBIL CHEM PATENTS INC (US) 2008-01-02 EP disclosed
US-7053153-B2 Ethylene copolymer compositions suitable for viscosity index improvers and lubricant compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-05-30 US disclosed
US-20040034168-A1 Ethylene copolymer compositions suitable for viscosity index improvers and lubricant compositions SCHAUDER JEAN-ROCH (BE) 2004-02-19 US disclosed
EP-1355961-A2 ETHYLENE COPOLYMER COMPOSITIONS SUITABLE FOR VISCOSITY INDEX IMPROVERS AND LUBRICANT COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2003-10-29 EP disclosed
EP-0775189-B1 LUBRICATING OILS COMPRISING LOW SATURATE BASESTOCK INFINEUM USA LP (US) 2003-01-22 EP disclosed
WO-2002046251-A2 ETHYLENE COPOLYMER COMPOSITIONS SUITABLE FOR VISCOSITY INDEX IMPROVERS AND LUBRICANT COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-06-13 WO disclosed
US-5932525-A INTERNAL COMBUSTION ENGINE MULTIGRADE LUBRICATING OIL CONTAINING A MIXTURE OF GREATER THAN 20% AROMATICS, LESS THAN 70% SATURATED HYDROCARBONS, ASHLESS DETERGENT, AND MULTIFUNCTIONAL VISCOSITY MODIFIER; ANTI-VARNISH AGENTS EXXON CHEMICAL PATENTS, INC. (US) 1999-08-03 US disclosed
EP-0673407-B1 MIXED ETHYLENE ALPHA OLEFIN COPOLYMER MULTIFUNCTIONAL VISCOSITY MODIFIERS USEFUL IN LUBE OIL COMPOSITIONS EXXON CHEMICAL PATENTS INC (US) 1998-10-07 EP disclosed
US-5744429-A FLOW CONTROL AGENTS EXXON CHEMICAL PATENTS INC (US) 1998-04-28 US disclosed
EP-0775189-A1 LUBRICATING OILS COMPRISING LOW SATURATE BASESTOCK EXXON CHEMICAL PATENTS INC. (US) 1997-05-28 EP disclosed
WO-1996039477-A1 LUBRICATING OILS COMPRISING LOW SATURATE BASESTOCK EXXON CHEMICAL PATENTS INC. (US) 1996-12-12 WO disclosed
US-5427702-A Mixture of copolymers with different amounts of ethylene functionalized with acid groups and nucleophilic amine EXXON CHEMICAL PATENTS INC. (US) 1995-06-27 US disclosed
US-5055213-A Addition copolymers containing maleic anhydride monomer modifi ed by a phenothiazine derivative, napthtylamine or diphenylami ne; antideposit agents; dispersants; oxidation resistance SOCIETE NATIONALE ELF AQUITAINE (FR) 1991-10-08 US disclosed
EP-0375503-A1 Additives to lubricants resulting from the condensation of an alkylene polyamine onto a copolymer having contiguous carboxylic groups ELF AQUITAINE (FR) 1990-06-27 EP disclosed