Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720734 | 0.92 | KMT2A (0.40) | HTTKMT2ANPSR1MEN1L3MBTL1 | |
| SCHEMBL457233 | 0.90 | KMT2A (0.32) | KMT2AMEN1L3MBTL1CA12CA1 | |
| SCHEMBL462003 | 0.90 | IDO1 (0.36) | HTTKMT2AL3MBTL1CA12CA1 | |
| SCHEMBL459152 | 0.86 | CTSS (0.36) | HTTKMT2ANPSR1MEN1L3MBTL1 | |
| SCHEMBL2013227 | 0.85 | CA12 (0.34) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL462095 | 0.85 | RORC (0.36) | HTTKMT2AL3MBTL1CA12CA1 | |
| SCHEMBL1726610 | 0.81 | KMT2A (0.37) | HTTKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2016334 | 0.81 | SLC6A2 (0.39) | KMT2ASLC6A2SLC6A4L3MBTL1 | |
| SCHEMBL2012019 | 0.80 | KDM1A (0.39) | KMT2AL3MBTL1CA12CA1CA7 | |
| SCHEMBL2226908 | 0.78 | KMT2A (0.36) | KMT2ASLC6A2SLC6A4SLC6A3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012066077-A1 | 1,4 DI SUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |