SCHEMBL4595020

SCHEMBL4595020

O=C(O)C(NC(C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 3/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ABCB11 O95342 1/20 0.35
F2 P00734 1/20 0.35
TP53 P04637 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
KMT2A Q03164 1/20 0.35
CYP2C19 P33261 1/20 0.35
DUSP3 P51452 1/20 0.35
PTPN5 P54829 1/20 0.35
PTPN11 Q06124 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3978169 0.79 TP53 (0.42) ALDH1A1LMNATP53MEN1MAPT
SCHEMBL3978172 0.79 TP53 (0.42) ALDH1A1LMNATP53MEN1MAPT
SCHEMBL23611031 0.77 TP53 (0.40) ALDH1A1LMNATP53MEN1MAPT
Lactic Acid SCHEMBL31468110 0.71 TP53 (0.55) ALDH1A1TSHRTP53
SCHEMBL20512334 0.71 TP53 (0.35) ALDH1A1TSHRTP53CA1CA2
SCHEMBL6000360 0.69
SCHEMBL3271137 0.69
SCHEMBL24042401 0.69 ALDH1A1 (0.41) ALDH1A1LMNATSHRTHRBRECQL
SCHEMBL24191854 0.67 LMNA (0.32) ALDH1A1LMNATSHRTHRBRECQL
SCHEMBL1421383 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0688816-A1 Low-color polymer ROHM AND HAAS COMPANY (US) 1995-12-27 EP claimed
US-7459496-B2 Coating compositions having improved stability LUBRIZOL ADVANCED MATERIALS, INC. (US) 2008-12-02 US disclosed
US-7417086-B2 desirably low level of yellowness, both when new and upon aging ROHM AND HAAS COMPANY (US) 2008-08-26 US disclosed
EP-1789486-B1 COATING COMPOSITIONS HAVING IMPROVED STABILITY LUBRIZOL ADVANCED MAT INC (US) 2008-01-09 EP disclosed
EP-1789486-A1 COATING COMPOSITIONS HAVING IMPROVED STABILITY Noveon, Inc. (US) 2007-05-30 EP disclosed
US-20060116453-A1 Coating compositions ROHM AND HAAS COMPANY 2006-06-01 US disclosed
EP-1502934-B1 Coating compositions ROHM & HAAS (US) 2006-05-10 EP disclosed
WO-2006026379-A1 COATING COMPOSITIONS HAVING IMPROVED STABILITY NOVEON, INC. (US) 2006-03-09 WO disclosed
US-20060047062-A1 Coating compositions having improved stability LUBRIZOL ADVANCED MATERIALS, INC. 2006-03-02 US disclosed
EP-1502934-A1 Coating compositions ROHM AND HAAS COMPANY (US) 2005-02-02 EP disclosed
EP-0778317-B1 Waterborne crosslinkable compositions ROHM & HAAS (US) 2003-03-19 EP disclosed
US-6512042-B1 Storage-stable, crosslinkable polymer compositions comprising: (a) an aqueous dispersion of a an acrylic polymer component containing certain carbonyl- containing functional-groups; (b) a nitrogen containing compound having at least two ROHM AND HAAS COMPANY 2003-01-28 US disclosed
EP-0778317-A2 Waterborne crosslinkable compositions ROHM AND HAAS COMPANY (US) 1997-06-11 EP disclosed
EP-0688816-A1 Low-color polymer ROHM AND HAAS COMPANY (US) 1995-12-27 EP disclosed