Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | AQP1 | P29972 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232748 | 0.86 | PRKAB2 (0.43) | LMNAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL4595207 | 0.83 | PTGDR2 (0.39) | MEN1KMT2APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6367411 | 0.82 | OXTR (0.43) | LMNAHTTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL4596631 | 0.82 | AQP1 (0.57) | LMNASMN1; SMN2TDP1L3MBTL1MEN1 | |
| SCHEMBL5141127 | 0.81 | AQP1 (0.41) | LMNAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL4596147 | 0.81 | OXTR (0.48) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL4232754 | 0.80 | AQP1 (0.41) | LMNAHTTSMN1; SMN2TDP1MEN1 | |
| SCHEMBL4220807 | 0.79 | AQP1 (0.58) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL4595205 | 0.78 | AQP1 (0.37) | MEN1KMT2APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4229679 | 0.78 | OXTR (0.42) | ALDH1A1MAPK1AQP1LPAR1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |