Mexenone

Mexenone

SCHEMBL4595243

COc1ccc(C(=O)c2ccc(C)cc2)c(O)c1.O=C(c1cccc(O)c1O)c1cccc(O)c1O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.66
LMNA P02545 4/20 0.66
CYP3A4 P08684 3/20 0.66
CYP1A2 P05177 2/20 0.66
PGR P06401 2/20 0.66
SLC6A2 P23975 2/20 0.66
CYP2C19 P33261 2/20 0.66
ALOX15 P16050 2/20 0.66
ADORA3 P0DMS8 1/20 0.66
AR P10275 1/20 0.66
CHRM1 P11229 1/20 0.66
TBXA2R P21731 1/20 0.66
ADRA1A P35348 1/20 0.66
HIF1A Q16665 1/20 0.66
ALDH1A1 P00352 5/20 0.64
HTT P42858 3/20 0.64
MAPK1 P28482 3/20 0.64
CYP2D6 P10635 1/20 0.64
PDE4A P27815 1/20 0.64
HRH1 P35367 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mexenone SCHEMBL15327784 0.92 HPGD (0.78) HPGDLMNACYP3A4CYP1A2PGR
Mexenone SCHEMBL39448 0.89 LMNA (0.74) HPGDLMNACYP3A4CYP1A2PGR
Mexenone SCHEMBL8017506 0.89 LMNA (0.74) HPGDLMNACYP3A4CYP1A2PGR
SCHEMBL1568890 0.89 LMNA (0.82) HPGDLMNACYP3A4CYP1A2PGR
Mexenone SCHEMBL29365598 0.89 LMNA (0.74) HPGDLMNACYP3A4CYP1A2PGR
Mexenone SCHEMBL29612353 0.88 LMNA (0.72) HPGDLMNACYP3A4CYP1A2PGR
Mexenone SCHEMBL6847100 0.87 LMNA (0.86) HPGDLMNACYP3A4CYP1A2PGR
SCHEMBL5134949 0.85 KMT2A (0.59) HPGDLMNACYP3A4CYP1A2PGR
Dioxybenzone SCHEMBL5161579 0.82 HPGD (0.88) HPGDLMNACYP3A4CYP1A2PGR
Dioxybenzone SCHEMBL4923214 0.82 HPGD (0.88) HPGDLMNACYP3A4CYP1A2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO disclosed