Mexenone

Mexenone

SCHEMBL6847100

COc1ccc(C(=O)c2ccc(C)cc2)c(O)c1.COc1ccc(C(=O)c2ccccc2)c(O)c1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.86
HPGD P15428 5/20 0.86
ALDH1A1 P00352 5/20 0.86
HTT P42858 4/20 0.86
CYP1A2 P05177 2/20 0.86
PGR P06401 2/20 0.86
SLC6A2 P23975 2/20 0.86
CYP2C19 P33261 2/20 0.86
MAPK1 P28482 2/20 0.86
CYP2D6 P10635 1/20 0.86
PDE4A P27815 1/20 0.86
HRH1 P35367 1/20 0.86
SLC6A3 Q01959 1/20 0.86
PDE4D Q08499 1/20 0.86
CYP3A4 P08684 3/20 0.64
ADORA3 P0DMS8 1/20 0.64
AR P10275 1/20 0.64
CHRM1 P11229 1/20 0.64
ALOX15 P16050 1/20 0.64
TBXA2R P21731 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mexenone SCHEMBL29365598 0.94 LMNA (0.74) LMNAHPGDALDH1A1HTTCYP1A2
Mexenone SCHEMBL8017506 0.94 LMNA (0.74) LMNAHPGDALDH1A1HTTCYP1A2
Mexenone SCHEMBL39448 0.94 LMNA (0.74) LMNAHPGDALDH1A1HTTCYP1A2
Mexenone SCHEMBL29612353 0.93 LMNA (0.72) LMNAHPGDALDH1A1HTTCYP1A2
Oxybenzone SCHEMBL6674080 0.93 HPGD (1.00) LMNAHPGDALDH1A1HTTCYP1A2
Oxybenzone SCHEMBL29355332 0.93 HPGD (1.00) LMNAHPGDALDH1A1HTTCYP1A2
Oxybenzone SCHEMBL419361 0.93 HPGD (1.00) LMNAHPGDALDH1A1HTTCYP1A2
Oxybenzone SCHEMBL5161586 0.93 HPGD (1.00) LMNAHPGDALDH1A1HTTCYP1A2
Oxybenzone SCHEMBL15551 0.93 HPGD (1.00) LMNAHPGDALDH1A1HTTCYP1A2
Mexenone SCHEMBL15327784 0.92 HPGD (0.78) LMNAHPGDALDH1A1HTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723720-A1 NEW POLYOL POLYRHAMNOSIDES, PROCESS FOR THE PREPARATION THEREOF, AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING SAME Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2020-10-21 EP disclosed
EP-3723719-A1 NEW GLYCERYL POLYRHAMNOSIDES, PROCESS FOR THE PREPARATION THEREOF, AND COSMETIC AND/OR PHARMACEUTICAL COMPOSITION COMPRISING SAME Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2020-10-21 EP disclosed
US-20040170670-A1 Cosmetic sponges REGENESIS LLC 2004-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170670-A1 Cosmetic sponges CUTA, SUCLG1, AQP3 LMNA 2236/4885HPGD 583/4885ALDH1A1 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.