SCHEMBL459533

SCHEMBL459533

CC(=O)c1ccc(OCC(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.66
GAA P10253 1/20 0.63
MAPT P10636 4/20 0.63
LMNA P02545 2/20 0.63
ALOX15 P16050 1/20 0.61
MAOB P27338 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.59
POLB P06746 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HPGD P15428 1/20 0.57
RAB9A P51151 1/20 0.57
ALDH1A1 P00352 3/20 0.56
FFAR1 O14842 1/20 0.55
TSHR P16473 1/20 0.54
NR4A1 P22736 1/20 0.54
APEX1 P27695 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL11658868 0.91 L3MBTL1 (0.56) L3MBTL1GAAMAPTLMNAALOX15
SCHEMBL12909782 0.86 L3MBTL1 (0.68) L3MBTL1GAAMAPTLMNAMAOB
SCHEMBL339492 0.85 ALOX15 (0.81) MAPTLMNAALOX15SMN1; SMN2ALDH1A1
SCHEMBL5321036 0.85 ALOX15 (0.57) MAPTALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL13889134 0.85 ALOX15 (0.57) MAPTALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL7463253 0.84 MAPT (0.68) L3MBTL1GAAMAPTLMNARAB9A
SCHEMBL5827387 0.83 ALOX15 (0.65) MAPTALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL29051537 0.83 ALOX15 (0.65) MAPTALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL341847 0.83 ALOX15 (0.65) MAPTALOX15SMN1; SMN2ALDH1A1FFAR1
SCHEMBL16035699 0.83 ALOX15 (0.65) GAAMAPTALOX15SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-9182385-B2 Methods for diagnosis, prognosis and methods of treatment NODALITY, INC. (US) 2015-11-10 US claimed
US-8778620-B2 Methods for diagnosis, prognosis and methods of treatment NODALITY, INC. (US) 2014-07-15 US claimed
US-20130130279-A1 METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT NODALITY, INC. (US) 2013-05-23 US claimed
US-20120309029-A1 METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT NODALITY, INC. (US) 2012-12-06 US claimed
US-8227202-B2 Methods for diagnosis, prognosis and methods of treatment NODALITY, INC. (US) 2012-07-24 US claimed
WO-2007059066-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2007-05-24 WO claimed
US-20070110844-A1 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. 2007-05-17 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-0159864-B1 METHOD OF MODIFYING TASTE TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1989-07-19 EP claimed
EP-0159864-A2 Method of modifying taste TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1985-10-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS L3MBTL1 1390/4885GAA 360/4885MAPT 2153/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS L3MBTL1 1390/4885GAA 360/4885MAPT 2153/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 L3MBTL1 598/4885GAA 1358/4885MAPT 4074/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 L3MBTL1 4695/4885GAA 958/4885MAPT 539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.