SCHEMBL4595438

SCHEMBL4595438

C=CCN(N)c1cc[nH]c(=O)n1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.31
▸ HPGD P15428 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8148663 0.74 ADRA2B (0.31) ALDH1A1KDM4ERAB9A
SCHEMBL2575583 0.73 ELANE (0.38) RAB9A
SCHEMBL18092899 0.70 PDPK1 (0.32) —
SCHEMBL18133228 0.70 KMT2A (0.42) KDM4E
SCHEMBL8840862 0.68 DYRK1A (0.32) —
SCHEMBL2115053 0.67 NCF1 (0.41) ALDH1A1KDM4ERAB9A
SCHEMBL30629629 0.67 PARP1 (0.33) ALDH1A1RAB9A
SCHEMBL31441038 0.67 PARP1 (0.33) ALDH1A1HPGDKDM4ERAB9A
SCHEMBL10699206 0.67 PARP1 (0.33) ALDH1A1RAB9A
SCHEMBL5823571 0.67 ADRA2B (0.31) ALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025038971-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 — — WO disclosed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 — — EP disclosed
WO-2015196128-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2015-12-23 — — WO disclosed
EP-1934376-A2 DNA MICROARRAY FOR RAPID IDENTIFICATION OF CANDIDA ALBICANS IN BLOOD CULTURES. UNIVERSITÄT ZU KÖLN (DE) 2008-06-25 — — EP disclosed
WO-2007039319-A2 DNA MICROARRAY FOR RAPID IDENTIFICATION OF CANDIDA ALBICANS IN BLOOD CULTURES UNIV KOELN (DE) 2007-04-12 — — WO disclosed
EP-1770171-A1 DNA microarray for rapid identification of Candida albicans in blood cultures. UNIVERSITÄT ZU KÖLN (DE) 2007-04-04 — — EP disclosed
Send feedback