Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | CDC25A | P30304 | 8/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14506483 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL7504905 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL7499946 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL18188988 | 0.77 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL10632834 | 0.76 | CDC25A (0.62) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL29131197 | 0.75 | CDC25A (0.60) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL3016301 | 0.75 | CDC25A (0.60) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL254004 | 0.74 | CDC25A (0.70) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| SCHEMBL28227485 | 0.74 | CDC25A (0.62) | ALDH1A1MEN1KMT2AHSD17B10CDC25A | |
| Hydrochloric Acid SCHEMBL7497399 | 0.74 | CDC25A (0.59) | ALDH1A1MEN1KMT2AHSD17B10CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008046083-A2 | USE OF OXINDOLE COMPOUNDS AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-04-17 | — | — | WO | disclosed |
| EP-1877378-A2 | OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-01-16 | — | — | EP | disclosed |
| US-20070105820-A1 | Oxindole compounds and their uses as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2007-05-10 | — | — | US | disclosed |
| WO-2006113864-A2 | OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105820-A1 | Oxindole compounds and their uses as therapeutic agents | OPRL1, OPRK1, TRPV1 | ALDH1A1 1136/4885MEN1 4040/4885KMT2A 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.