SCHEMBL4595773

SCHEMBL4595773

CC1(C)C=CC(C=Cc2ccccc2)=CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHAT P28329 2/20 0.39
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TTR P02766 1/20 0.37
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
RELA Q04206 1/20 0.35
TRPA1 O75762 1/20 0.35
MAOB P27338 2/20 0.34
NFE2L2 Q16236 1/20 0.34
CYP19A1 P11511 1/20 0.34
MAOA P21397 1/20 0.34
KDM4E B2RXH2 2/20 0.34
GMNN O75496 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
BLM P54132 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30781477 1.00 CHAT (0.39) CHATMEN1MAPTKMT2ANPSR1
SCHEMBL7941862 0.83 CHAT (0.37) CHATMEN1MAPTKMT2ANPSR1
SCHEMBL29217549 0.82 RELA (0.40) CHATMEN1MAPTKMT2ANPSR1
SCHEMBL7006726 0.81 TRPA1 (0.39) CHATMEN1MAPTKMT2ANPSR1
SCHEMBL4438933 0.81 MAOB (0.39) CHATMEN1KMT2ATTRALOX5
SCHEMBL11210851 0.80 RELA (0.41) CHATMEN1MAPTKMT2ANPSR1
SCHEMBL6837817 0.79 CHAT (0.35) CHATMEN1MAPTKMT2ATTR
SCHEMBL31506486 0.79 CHAT (0.35) CHATMEN1MAPTKMT2ATTR
Hydrochloric Acid SCHEMBL12003783 0.79 MAOB (0.38) CHATMEN1KMT2ATTRALOX5
SCHEMBL28484538 0.79 CHAT (0.39) CHATMEN1KMT2ATTRALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486241-A Preparation of battery grade lithium hydroxide from lithium-containing raffinate 安徽南都华铂新材料科技有限公司 2024-02-02 CN disclosed
EP-1493779-B1 OPTICAL DISK SUBSTRATE AND LIGHTGUIDE PLATE TEIJIN CHEMICALS LTD (JP) 2008-01-16 EP disclosed
US-7205375-B2 Optical disk substrate and lightguide plate TEIJIN CHEMICALS, LTD. (JP) 2007-04-17 US disclosed
US-20050106350-A1 Optical disk substrate and lightguide plate TEIJIN CHEMICALS, LTD. (JP) 2005-05-19 US disclosed
EP-1493779-A1 OPTICAL DISK SUBSTRATE AND LIGHTGUIDE PLATE Teijin Chemicals, Ltd. (JP) 2005-01-05 EP disclosed
US-6787671-B2 FOR PRODUCTION OF ALDEHYDES, CARBOXYLIC ACIDS, ESTERS, OR KETONES VIA REACTION OF OSMIUM CATALYST AND PEROXYMONOSULFURIC ACID BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2004-09-07 US disclosed
US-20030149299-A1 Catalytic osmium-assisted oxidative cleavage of olefins BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY 2003-08-07 US disclosed
WO-2003060852-A2 CATALYTIC OSMIUM-ASSISTED OXIDATIVE CLEAVAGE OF OLEFINS MICHIGAN STATE UNIVERSITY (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149299-A1 Catalytic osmium-assisted oxidative cleavage of olefins OXER1, OXSR1, AOX1 CHAT 2462/4885MEN1 4234/4885MAPT 3777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.