SCHEMBL4595983

SCHEMBL4595983

CC(C)(C)c1ccc(CCl)nn1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12668138 0.86 HPGD (0.32) HPGDTSHRALDH1A1
SCHEMBL45880 0.80
SCHEMBL19297893 0.78
SCHEMBL30721121 0.78 TRPV4 (0.34) ALDH1A1
SCHEMBL7999604 0.78 TRPV4 (0.34) ALDH1A1
SCHEMBL47578 0.78 TSHR (0.38) HPGDTSHRALDH1A1
SCHEMBL3293340 0.78 ALDH1A1 (0.41) ALDH1A1
SCHEMBL20207721 0.75 NOS3 (0.32) ALDH1A1
SCHEMBL12756344 0.75
SCHEMBL12829578 0.74 KCNH2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1555259-B1 Malononitrile compounds as pesticides SUMITOMO CHEMICAL CO (JP) 2008-01-02 EP disclosed
EP-1555259-A1 Malononitrile compounds as pesticides Sumitomo Chemical Company, Limited (JP) 2005-07-20 EP disclosed