Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797849 | 0.85 | POLB (0.41) | POLBHTTGABRA1GABRB2GAA | |
| SCHEMBL1412111 | 0.85 | ALDH1A1 (0.52) | POLBALDH1A1MAPT | |
| SCHEMBL29199935 | 0.85 | POLB (0.33) | POLBHTTALDH1A1MAPT | |
| SCHEMBL28883400 | 0.82 | NR4A2 (0.48) | ALDH1A1 | |
| SCHEMBL1556062 | 0.77 | NCEH1 (0.45) | POLBGAAALDH1A1MAPT | |
| SCHEMBL393531 | 0.76 | POLB (0.35) | POLBHTTGABRA1GABRB2CTRC | |
| SCHEMBL833911 | 0.75 | TYR (0.44) | HTTGABRA1GABRB2GAACTRC | |
| SCHEMBL262868 | 0.74 | GABRA1 (0.55) | POLBHTTGABRA1GABRB2GAA | |
| SCHEMBL1332031 | 0.74 | GABRA1 (0.55) | POLBHTTGABRA1GABRB2GAA | |
| SCHEMBL23457998 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11965054-B2 | Storage-stable pigmented isocyanate group-containing formulations with isocyanate group-containing grinding resin and use thereof | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2024-04-23 | — | — | US | disclosed |
| CN-113518791-B | Storage-stable pigment-containing isocyanate-group-containing formulations having an isocyanate-group-containing grinding resin and use thereof | 科思创知识产权两合公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-112020528-B | Storage-stable, pigmented, isocyanate group-containing formulations and use thereof | 科思创知识产权两合公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110446737-B | Formation of coatings by separate application of polyisocyanate composition and crosslinking catalyst | 科思创德国股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3931234-A1 | STORAGE-STABLE PIGMENTED ISOCYANATE GROUP-CONTAINING FORMULATIONS WITH ISOCYANATE GROUP-CONTAINING GRINDING RESIN AND USE THEREOF | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-01-05 | — | — | EP | disclosed |
| CN-113518791-A | Storage-stable, pigment-containing formulations containing isocyanate groups with abrasive resins containing isocyanate groups and use thereof | 科思创知识产权两合公司 | 2021-10-19 | — | — | CN | disclosed |
| US-20210102090-A1 | FORMATION OF COATINGS BY SEPARATE APPLICATION OF POLYISOCYANATE COMPOSITIONS AND CROSSLINKING CATALYSTS | COVESTRO DEUTSCHLAND AG (DE) | 2021-04-08 | — | — | US | disclosed |
| EP-3765545-A1 | STORAGE-STABLE PIGMENTED FORMULATIONS CONTAINING ISOCYANATE GROUPS AND USE THEREOF | Covestro Intellectual Property GmbH & Co. KG (DE) | 2021-01-20 | — | — | EP | disclosed |
| US-20200407576-A1 | STORAGE-STABLE PIGMENTED FORMULATIONS CONTAINING ISOCYANATE GROUPS AND USE THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2020-12-31 | — | — | US | disclosed |
| CN-112020528-A | Storage-stable, pigmented, isocyanate group-containing formulations and use thereof | 科思创知识产权两合公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-2393859-A1 | TWO-COMPONENT COATING COMPOSITIONS FOR FLEXIBLE COATINGS | Bayer MaterialScience AG (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-20110294934-A1 | TWO-COMPONENT COATING COMPOSITIONS FOR FLEXIBLE COATINGS | BAYER MATERIAL SCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110288217-A1 | COATINGS WHICH ARE BASED ON ALLOPHANATE GROUP-CONTAINING POLYISOCYANATES | Bayer MaterialScience AG Law and Patents (DE) | 2011-11-24 | — | — | US | disclosed |
| WO-2010089034-A1 | TWO-COMPONENT COATING COMPOSITIONS FOR FLEXIBLE COATINGS | BAYER MATERIALSCIENCE AG (DE) | 2010-08-12 | — | — | WO | disclosed |
| US-RE34669-E | Method for preparing moulded polyureapolyurethane flexible foams | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-07-19 | — | — | US | disclosed |
| EP-0371680-B1 | Method for preparing polyurea-polyurethane flexible foams | ICI PLC (GB) | 1993-12-22 | — | — | EP | disclosed |
| US-5034427-A | Forming a polurea, polyurethane by polymerization of polyisocyanate and polyol and a diamine chain extender | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-07-23 | — | — | US | disclosed |
| EP-0371680-A1 | Method for preparing polyurea-polyurethane flexible foams | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-06 | — | — | EP | disclosed |
| US-4880872-A | POLYUREAS, POLYURETHANES | ICI AMERICAS INC. (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0248628-A2 | Polyurea-Polyurethane from the reaction of a polyol, an aromatic amine and an isocyanate terminated polyoxy-propylene prepolymer | ICI AMERICAS INC. (US) | 1987-12-09 | — | — | EP | disclosed |