SCHEMBL833911

SCHEMBL833911

CCCCc1ccc2c(N)c(CCCC)ccc2c1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.44
TLR8 Q9NR97 4/20 0.41
CTRC Q99895 1/20 0.40
SKP2 Q13309 1/20 0.38
CYP3A4 P08684 2/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 1/20 0.37
TP53 P04637 1/20 0.37
ALOX5 P09917 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 2/20 0.37
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
GLA P06280 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL840920 0.88 TYR (0.48) TYRTLR8CTRCSKP2CYP3A4
SCHEMBL4657033 0.87 ALDH1A1 (0.45) TYRTLR8SKP2CYP3A4MAPT
SCHEMBL4423913 0.81 TYR (0.48) TYRTLR8CYP3A4MAPTMEN1
SCHEMBL1406259 0.81 TLR8 (0.49) TLR8CYP3A4MAPTMEN1HTT
SCHEMBL3676124 0.79 TLR8 (0.46) TYRTLR8CYP3A4ALOX5CYP2C9
SCHEMBL1232399 0.78 SKP2 (0.44) TYRTLR8CTRCSKP2CYP3A4
SCHEMBL24677644 0.77 TYR (0.40) TYRTLR8CTRCSKP2CYP3A4
SCHEMBL1498626 0.77 SKP2 (0.47) TYRTLR8CTRCSKP2CYP3A4
SCHEMBL842068 0.77 TYR (0.40) TYRTLR8CTRCSKP2CYP3A4
SCHEMBL10342533 0.77 SKP2 (0.47) TYRTLR8CTRCSKP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5059672-A Polyurea coatings; high tensile strength, chemical and corrosion resistant THARE COAT, INC. (US) 1991-10-22 US claimed
EP-3144728-B1 TONER BINDER, AND TONER SANYO CHEMICAL IND LTD (JP) 2021-04-21 EP disclosed
US-20210002441-A1 RESIN PARTICLES AND METHOD FOR PRODUCING SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2021-01-07 US disclosed
CN-111240165-A Toner binder and toner 三洋化成工业株式会社 2020-06-05 CN disclosed
CN-106462094-B Toner binder and toner 三洋化成工业株式会社 2020-05-01 CN disclosed
CN-105431783-B Toner binder and toner 三洋化成工业株式会社 2019-08-02 CN disclosed
US-10114304-B2 Toner binder, and toner SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-10-30 US disclosed
US-10007207-B2 Liquid developer and method for manufacturing the same Konica Minolta, Inc. (JP) 2018-06-26 US disclosed
US-20180164708-A1 TONER BINDER, AND TONER SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-06-14 US disclosed
US-9921505-B2 Toner binder, and toner SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-20 US disclosed
EP-0219709-B1 POLYMETHYLENE POLYPHENYLAMINE MODIFIED DIAMINE CHAIN EXTENDERS AND POLYUREA ELASTOMERS THEREFROM THE DOW CHEMICAL COMPANY (US) 1989-11-23 EP disclosed
EP-0245864-A2 Cyclohexanedimethanol/diamine mixtures as RIM extenders THE DOW CHEMICAL COMPANY (US) 1987-11-19 EP disclosed
EP-0219709-A2 Polymethylene polyphenylamine modified diamine chain extenders and polyurea elastomers therefrom THE DOW CHEMICAL COMPANY (US) 1987-04-29 EP disclosed
US-4659747-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1987-04-21 US disclosed
EP-0075130-B1 IMPROVED REACTION INJECTION MOLDING PROCESS THE DOW CHEMICAL COMPANY (US) 1986-09-17 EP disclosed
EP-0185369-A2 Polyamide-polyurea polymers THE DOW CHEMICAL COMPANY (US) 1986-06-25 EP disclosed
US-4552945-A REACTION INJECTION MOLDING, POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1985-11-12 US disclosed
EP-0075130-A2 Improved reaction injection molding process THE DOW CHEMICAL COMPANY (US) 1983-03-30 EP disclosed
US-4374210-A MOLDING MATERIALS; LONG GELATION TIME; STOICHIOMETRY; INJECTION MOLDING THE UPJOHN COMPANY (US) 1983-02-15 US disclosed
US-4296212-A MOLDING MATERIALS THE UPJOHN COMPANY (US) 1981-10-20 US disclosed