SCHEMBL4596070

SCHEMBL4596070

Cc1ccc(C(=O)c2ccc3nc4ccc(C(=O)c5ccc(C)c(C)c5)cc4c(-c4ccc(C)c(C)c4)c3c2)cc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 1/20 0.49
ALDH1A1 P00352 6/20 0.44
NPC1 O15118 3/20 0.44
POLB P06746 3/20 0.44
MITF O75030 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAP3K14 Q99558 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
AURKA O14965 1/20 0.41
AURKB Q96GD4 1/20 0.41
HPGD P15428 3/20 0.40
RAB9A P51151 3/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29660586 1.00 CHEK2 (0.49) CHEK2SMN1; SMN2HTTALDH1A1NPC1
SCHEMBL10441496 0.76 ALDH1A1 (0.51) SMN1; SMN2HTTALDH1A1NPC1LMNA
SCHEMBL30543769 0.75 MAPT (0.51) SMN1; SMN2HTTALDH1A1NPC1POLB
SCHEMBL4595649 0.75 MAPT (0.51) SMN1; SMN2HTTALDH1A1NPC1POLB
SCHEMBL47827 0.75 SMN1; SMN2 (0.79) SMN1; SMN2HTTALDH1A1NPC1POLB
SCHEMBL29514906 0.75 SMN1; SMN2 (0.79) SMN1; SMN2HTTALDH1A1NPC1POLB
SCHEMBL4595823 0.73 MAPT (0.50) CHEK2SMN1; SMN2HTTALDH1A1NPC1
SCHEMBL30543784 0.73 MAPT (0.50) CHEK2SMN1; SMN2HTTALDH1A1NPC1
SCHEMBL822303 0.73 SMN1; SMN2 (0.83) CHEK2SMN1; SMN2HTTALDH1A1NPC1
SCHEMBL8972079 0.73 NPC1 (0.51) ALDH1A1NPC1POLBLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
EP-1877864-B1 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF MERCK PATENT GMBH (DE) 2018-09-19 EP disclosed
EP-3339331-A1 COMPOSITION Adeka Corporation (JP) 2018-06-27 EP disclosed
WO-2013064890-A2 NANOCOMPOSITE NEGATIVE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-05-10 WO disclosed
US-20130105440-A1 NANOCOMPOSITE NEGATIVE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-05-02 US disclosed
EP-1877864-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ Electronic Materials USA Corp. (US) 2008-01-16 EP disclosed
US-7247419-B2 Nanocomposite photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2007-07-24 US disclosed
US-20070141510-A1 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF CHEN CHUNWEI 2007-06-21 US disclosed
WO-2006109121-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2006-10-19 WO disclosed
US-20060228645-A1 Nanocomposite photosensitive composition and use thereof MERCK PATENT GMBH (DE) 2006-10-12 US disclosed
US-7078157-B2 Photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2006-07-18 US disclosed
EP-1602010-A2 PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ Electronic Materials USA Corp. (US) 2005-12-07 EP disclosed
WO-2004077153-A2 PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (US) 2004-09-10 WO disclosed
US-20040175653-A1 Photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. 2004-09-09 US disclosed
EP-0374704-B1 Photopolymerisable blend and photopolymerisable recording material containing it MORTON INT INC (US) 1996-03-27 EP disclosed
US-5217845-A 9-Arylacridine as photoinitiator HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-08 US disclosed