SCHEMBL4596290

SCHEMBL4596290

C=C(C)C(=O)OC(CC)O[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11804123 0.91 TSHR (0.34) TSHRALDH1A1THRB
Tromethamine SCHEMBL20506918 0.88 TSHR (0.30) TSHR
SCHEMBL3803729 0.86 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL3990899 0.85 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL601418 0.84 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL8864054 0.84 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL649933 0.82 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL5068871 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL9162961 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL27982283 0.81 TSHR (0.39) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114173748-B Polymer film agent having excellent water-repellent and oil-repellent properties at the same time, and cosmetic composition having excellent makeup durability comprising the same 株式会社LG生活健康 2024-03-08 CN disclosed
EP-1137727-B1 AQUEOUS COATING COMPOSITIONS DU PONT (US) 2008-01-09 EP disclosed
EP-1619225-A2 Aqueous pigment dispersion E.I.Du pont de nemours and company (US) 2006-01-25 EP disclosed
CN-1175070-C Pigment dispersions containing hydroxylated AB-block polymer dispersants 纳幕尔杜邦公司 2004-11-10 CN disclosed
EP-1240255-B1 PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT DU PONT (US) 2004-09-22 EP disclosed
EP-0996689-B1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT DU PONT (US) 2002-12-18 EP disclosed
EP-1240255-A2 PIGMENT DISPERSIONS CONTAINING ABC-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-09-18 EP disclosed
US-6413306-B1 GROUP TRANSFER POLYMERIZATION OF ACRYLATES, AMINOACRYLATES, AND HYDROXYACRYLATES; QUATERNIZATION; BONDING WITH PRIMER TO IMPROVE INTERCOAT ADHESION WITH BASE COAT; NONFLAKING, NONCHIPPING; AUTOMOBILES, TRUCKS E. I. DU PONT DE NEMOURS AND COMPANY 2002-07-02 US disclosed
US-6306521-B1 SUBSTRATE COATED WITH DRIED, CURED LAYER OF COMPOSITION OF ORGANIC LIQUID CARRIER, FILM FORMING BINDER AND PIGMENT DISPERSION, WHEREIN PIGMENT DISPERSION COMPRISES DISPERSED PIGMENT, CARRIER LIQUID AND AB-BLOCK POLYMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY 2001-10-23 US disclosed
EP-1137727-A1 AQUEOUS COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-04 EP disclosed
CN-1264413-A Pigment dispersions containing hydroxylated AB-block polymer dispersant DU PONT (US) 2000-08-23 CN disclosed
WO-2000026308-A1 AQUEOUS COATING COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-11 WO disclosed
EP-0996689-A1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-03 EP disclosed
WO-1999003938-A1 PIGMENT DISPERSIONS CONTAINING HYDROXYLATED AB-BLOCK POLYMER DISPERSANT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-28 WO disclosed
US-5859113-A COATINGS; POLYMER A SEGMENT CONSISTS OF POLYMERIZED GLYCIDYL (METH)ACRYLATE REACTED WITH AN ACID; POLYMER B SEGMENT CONTAINS REACTIVE HYDROXY ALKYL (METH)ACRYLATE MONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-12 US disclosed
US-5658988-A ONE-PACKAGE; AUTOMOBILE FINISHES KANSAI PAINT CO., LTD. (JP) 1997-08-19 US disclosed
EP-0525064-A4 1994-04-06 EP disclosed
EP-0525064-A1 NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE CONTACT LENSES PERMEABLE TECHNOLOGIES, INC. (US) 1993-02-03 EP disclosed
WO-1991015527-A1 NOVEL SILICONE-CONTAINING POLYMERS AND OXYGEN PERMEABLE CONTACT LENSES PERMEABLE CONTACT LENSES, INC. (US) 1991-10-17 WO disclosed
US-3935342-A POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-27 US disclosed