Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596290 | 0.85 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL601418 | 0.84 | TSHR (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL8864054 | 0.84 | TSHR (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL649933 | 0.82 | ALDH1A1 (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL5068871 | 0.82 | TSHR (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL9162961 | 0.82 | TSHR (0.43) | TSHRALDH1A1THRB | |
| SCHEMBL10456434 | 0.81 | TSHR (0.34) | TSHRALDH1A1THRB | |
| SCHEMBL27753214 | 0.81 | THRB (0.36) | TSHRALDH1A1THRB | |
| SCHEMBL28528795 | 0.80 | TSHR (0.42) | TSHRALDH1A1THRB | |
| SCHEMBL27545799 | 0.80 | ALDH1A1 (0.35) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064291-B1 | FILLERS, PIGMENTS AND MINERAL POWDERS TREATED WITH ORGANOPOLYSILOXANES | DOW CORNING (US) | 2017-02-22 | — | — | EP | disclosed |
| US-9115285-B2 | Fillers, pigments and mineral powders treated with organopolysiloxanes | DOW CORNING CORPORATION (US) | 2015-08-25 | — | — | US | disclosed |
| US-20090318614-A1 | Fillers, Pigments and Mineral Powders Treated With Organopolysiloxanes | DOW SILICONES CORPORATION | 2009-12-24 | — | — | US | disclosed |
| EP-2064291-A1 | FILLERS, PIGMENTS AND MINERAL POWDERS TREATED WITH ORGANOPOLYSILOXANES | Dow Corning Corporation (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008034806-A1 | FILLERS, PIGMENTS AND MINERAL POWDERS TREATED WITH ORGANOPOLYSILOXANES | DOW CORNING CORPORATION (US) | 2008-03-27 | — | — | WO | disclosed |