Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542146 | 0.98 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL8361113 | 0.88 | LMNA (0.77) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL29051501 | 0.81 | LMNA (0.63) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL8361111 | 0.81 | LMNA (0.68) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9584980 | 0.81 | MEN1 (0.68) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL4486860 | 0.81 | MEN1 (0.68) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL4596398 | 0.81 | LMNA (0.68) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL812387 | 0.80 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9542160 | 0.80 | MEN1 (0.71) | LMNAMEN1KMT2AKDM4EALOX15 | |
| SCHEMBL9001814 | 0.80 | LMNA (0.66) | LMNAMEN1KMT2AKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223539-A | Antagonist of platelet activating factor | G. D. SEARLE & CO. (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993010077-A1 | N,N-DI-ALKYL(PHENOXY)BENZAMIDE DERIVATIVES | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |