Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595116 | 0.86 | PARP1 (0.44) | ALDH1A1PARP1KDM4EPOLBMAOA | |
| SCHEMBL4596760 | 0.81 | MAPT (0.43) | ALDH1A1HPGDATMALOX15TP53 | |
| SCHEMBL10852030 | 0.80 | PARP1 (0.54) | ALDH1A1PARP1HPGDHSD17B10KDM4E | |
| SCHEMBL4230267 | 0.77 | PRKAB2 (0.45) | ALDH1A1HPGDATMALOX15TP53 | |
| SCHEMBL11039537 | 0.76 | PARP1 (0.54) | ALDH1A1PARP1MAPTGAAKDM4E | |
| SCHEMBL19122972 | 0.72 | PARP1 (0.56) | ALDH1A1PARP1HPGDTSHRHSD17B10 | |
| SCHEMBL13074639 | 0.72 | PARP1 (0.56) | ALDH1A1PARP1HPGDTSHRHSD17B10 | |
| SCHEMBL9050631 | 0.72 | PARP1 (0.52) | ALDH1A1PARP1TP53HSD17B10MAPT | |
| SCHEMBL11093468 | 0.70 | PARP1 (0.54) | ALDH1A1PARP1SMN1; SMN2CREBBPBRD4 | |
| SCHEMBL5544997 | 0.70 | MAOA (0.62) | PARP1MAOAMAOBHTR1AOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |