Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 3/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4764345 | 0.90 | AQP1 (0.56) | AQP1PARP1L3MBTL1BRD4HTR1A | |
| SCHEMBL4713102 | 0.88 | AQP1 (0.54) | AQP1PARP1L3MBTL1BRD4HTR1A | |
| SCHEMBL4596815 | 0.86 | PARP1 (0.47) | AQP1PARP1BRD4CREBBP | |
| SCHEMBL4596825 | 0.86 | AQP1 (0.52) | AQP1PARP1L3MBTL1AGPAT2IDO1 | |
| SCHEMBL4712234 | 0.85 | AQP1 (0.67) | AQP1PARP1BRD4HTR1ACREBBP | |
| SCHEMBL4230928 | 0.84 | AQP1 (0.76) | AQP1PARP1L3MBTL1AGPAT2SLC6A4 | |
| SCHEMBL5605564 | 0.84 | AQP1 (0.56) | AQP1L3MBTL1AGPAT2IDO1 | |
| SCHEMBL14113171 | 0.84 | AQP1 (0.76) | AQP1PARP1L3MBTL1AGPAT2SLC6A4 | |
| SCHEMBL4230233 | 0.84 | AQP1 (0.59) | AQP1L3MBTL1AGPAT2PDE2APDE10A | |
| SCHEMBL4606791 | 0.84 | AQP1 (0.47) | AQP1PARP1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |