Urea

Urea

SCHEMBL4597155

CCC(O)(O)O.NC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
TDP1 Q9NUW8 5/20 0.43
LMNA P02545 4/20 0.43
OR51E2 Q9H255 1/20 0.43
ALOX15 P16050 3/20 0.38
BLM P54132 2/20 0.38
PMP22 Q01453 2/20 0.38
CYP1A2 P05177 2/20 0.33
FFAR3 O14843 1/20 0.33
MEN1 O00255 1/20 0.33
THRB P10828 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 2/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL4457083 0.84 ACHE (0.41) ALDH1A1TDP1LMNAALOX15BLM
Urea SCHEMBL27439426 0.83 ALDH1A1 (0.40) ALDH1A1TDP1LMNAOR51E2ALOX15
SCHEMBL220594 0.80
Acrylamide SCHEMBL150558 0.80 ALDH1A1 (0.58) ALDH1A1LMNAALOX15THRBTSHR
Acetic Acid SCHEMBL3711197 0.79 FFAR3 (0.50) ALDH1A1TDP1LMNACYP1A2FFAR3
Acetic Acid SCHEMBL8189186 0.79 FFAR3 (0.50) ALDH1A1TDP1LMNACYP1A2FFAR3
Potassium SCHEMBL30589299 0.76
SCHEMBL30589300 0.76
Phosphine SCHEMBL29127621 0.76
Ethane SCHEMBL2448556 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1907471-A2 CELLUOSIC PRODUCTS COMPRISING SUBSTANTIALLY VOC-FREE COMPOSITIONS EverTech LLC (US) 2008-04-09 EP claimed
US-20070082187-A1 Celluosic products comprising substantially voc-free compositions CHEMCO, INC. 2007-04-12 US claimed
WO-2007002733-A2 CELLUOSIC PRODUCTS COMPRISING SUBSTANTIALLY VOC-FREE COMPOSITIONS CHEMCO, INC. (US) 2007-01-04 WO claimed
EP-1907471-A2 CELLUOSIC PRODUCTS COMPRISING SUBSTANTIALLY VOC-FREE COMPOSITIONS EverTech LLC (US) 2008-04-09 EP disclosed
WO-2007002733-A3 CELLUOSIC PRODUCTS COMPRISING SUBSTANTIALLY VOC-FREE COMPOSITIONS CHEMCO INC (US) 2007-12-21 WO disclosed
WO-2007002733-A2 CELLUOSIC PRODUCTS COMPRISING SUBSTANTIALLY VOC-FREE COMPOSITIONS CHEMCO, INC. (US) 2007-01-04 WO disclosed