Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isophthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | UNG | P13051 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL1028475 | 0.89 | SMN1; SMN2 (0.54) | KMT2AHPGDMEN1AKR1C3ALDH1A1 | |
| Isophthalic Acid SCHEMBL27573445 | 0.88 | CA12 (0.52) | CA12CA1CA2CA6CA9 | |
| Benzoic Acid SCHEMBL64441 | 0.87 | TSHR (0.64) | KMT2AHPGDMEN1KDM4EALDH1A1 | |
| Isophthalic Acid SCHEMBL9575080 | 0.87 | CA12 (0.60) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL1483205 | 0.85 | KMT2A (0.61) | CA12CA1CA2CA6CA9 | |
| SCHEMBL16366609 | 0.83 | MEP1B (0.65) | CA1CA2UNGFOLH1PKM | |
| SCHEMBL13702421 | 0.82 | SMN1; SMN2 (0.59) | KMT2APKML3MBTL1CYP1A2HSD17B10 | |
| Terephthalic Acid SCHEMBL31728724 | 0.82 | ALDH1A1 (0.60) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL680956 | 0.82 | CA12 (0.60) | CA12CA1CA2CA6CA9 | |
| Isophthalic Acid SCHEMBL28375462 | 0.82 | CA12 (0.60) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955498-B | Polybenzimidazole (PBI) membrane for redox flow battery | 南卡罗来纳大学 | 2024-05-10 | — | — | CN | claimed |
| EP-3850698-A2 | LOW PERMEABILITY POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES | University of South Carolina (US) | 2021-07-21 | — | — | EP | claimed |
| EP-3850697-A1 | POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES | University of South Carolina (US) | 2021-07-21 | — | — | EP | claimed |
| CN-112955498-A | Polybenzimidazole (PBI) membranes for redox flow batteries | 南卡罗来纳大学 | 2021-06-11 | — | — | CN | claimed |
| CN-112956056-A | Low permeability Polybenzimidazole (PBI) membranes for redox flow batteries | 南卡罗来纳大学 | 2021-06-11 | — | — | CN | claimed |
| EP-2443176-B1 | METHOD FOR THE PRODUCTION OF A HIGH-MOLECULAR POLYAZOLE | BASF SE (DE) | 2020-06-03 | — | — | EP | claimed |
| WO-2020056275-A1 | POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES | UNIVERSITY OF SOUTH CAROLINA (US) | 2020-03-19 | — | — | WO | claimed |
| WO-2020056268-A2 | LOW PERMEABILITY POLYBENZIMIDAZOLE (PBI) MEMBRANES FOR REDOX FLOW BATTERIES | UNIVERSITY OF SOUTH CAROLINA (US) | 2020-03-19 | — | — | WO | claimed |
| EP-2804889-B1 | PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS | BASF SE (DE) | 2019-03-13 | — | — | EP | claimed |
| US-20180123155-A1 | PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS | BASF SE (DE) | 2018-05-03 | — | — | US | claimed |
| US-20060057449-A1 | Proton-conducting membrane and the use thereof | BASF FUEL CELL GMBH (DE) | 2006-03-16 | — | — | US | claimed |
| US-20060035095-A1 | Proton-conducting membrane and use thereof verwendung | PEMEAS GMBH (DE) | 2006-02-16 | — | — | US | claimed |
| US-20060008690-A1 | Proton conducting polymer membrane comprising phoshphonic acid groups containing polyazoles and the use thereof in fuel cells | BASF FUEL CELL GMBH (DE) | 2006-01-12 | — | — | US | claimed |
| EP-1527493-B1 | PROTON-CONDUCTING POLYMER MEMBRANE COMPRISING A POLYMER WITH PHOSPHONIC ACID GROUPS AND USE THEREOF IN FUEL CELLS | PEMEAS GMBH (DE) | 2006-01-04 | — | — | EP | claimed |
| EP-1527494-B1 | PROTON-CONDUCTING POLYMER MEMBRANE COMPRISING A POLYMER WITH SULPHONIC ACID GROUPS AND USE THEREOF IN FUEL CELLS | PEMEAS GMBH (DE) | 2005-12-28 | — | — | EP | claimed |
| US-20050256296-A1 | Polymer film based on polyazoles, and uses thereof | BASF FUEL CELL GMBH (DE) | 2005-11-17 | — | — | US | claimed |
| US-20050244694-A1 | Proton-conducting polymer membrane comprising polymers containing phosphonic acid groups and its use in fuel cells | PEMEAS GMBH (DE) | 2005-11-03 | — | — | US | claimed |
| US-20050244695-A1 | vinyl-containing sulfonic acid polymerized in presence of one or more aromatic tetraamino compounds and with one or more aromatic carboxylic acids, their esters, their acid halides or their acid anhydrides; interpenetrating polymer network | BASF FUEL CELL GMBH (DE) | 2005-11-03 | — | — | US | claimed |
| US-20040127588-A1 | Proton-conducting membrane and use thereof | BASF FUEL CELL GMBH (DE) | 2004-07-01 | — | — | US | claimed |
| US-20040096734-A1 | Proton-comducting membrane and the use thereof | BASF FUEL CELL GMBH (DE) | 2004-05-20 | — | — | US | claimed |