Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737052 | 0.88 | KDM4E (0.66) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL328392 | 0.84 | RAB9A (0.47) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL4598049 | 0.83 | KDM4E (0.56) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL2898810 | 0.82 | MEN1 (0.58) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL12102113 | 0.81 | KDM4E (0.54) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL17427864 | 0.81 | KDM4E (0.54) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL778928 | 0.81 | MEN1 (0.64) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL4598208 | 0.81 | KDM4E (0.54) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL8306130 | 0.81 | KDM4E (0.53) | KDM4ERAB9ANPC1MEN1KMT2A | |
| SCHEMBL16186353 | 0.81 | KDM4E (0.50) | KDM4ERAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969332-B2 | Aryloxy dihalopropenyl ether compounds and uses thereof | SINOCHEM CORPORATION (CN) | 2015-03-03 | — | — | US | disclosed |
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2013-11-14 | — | — | US | disclosed |
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070066624-A1 | Chemokine receptor binding compounds | ANORMED, INC. (CA) | 2007-03-22 | — | — | US | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303541-A1 | ARYLOXY DIHALOPROPENYL ETHER COMPOUNDS AND USES THEREOF | DDT, CYP4B1, AADAC | KDM4E 243/4885RAB9A 3392/4885NPC1 2682/4885 |
| US-20070066624-A1 | Chemokine receptor binding compounds | CCR5, CCR4, CCR1 | KDM4E 3689/4885RAB9A 2707/4885NPC1 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.