Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457840 | 0.84 | CYP3A4 (0.42) | POLBL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL6512161 | 0.78 | L3MBTL1 (0.46) | POLBL3MBTL1GAAMAPTALDH1A1 | |
| SCHEMBL10723623 | 0.78 | CA12 (0.46) | POLBMEN1KMT2AGAAMAPT | |
| SCHEMBL3699457 | 0.76 | CCNT1 (0.36) | L3MBTL1MAPTCYP3A4ALDH1A1CYP1A2 | |
| SCHEMBL17263482 | 0.75 | CYP1A2 (0.35) | POLBL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL10044606 | 0.74 | CYP1A2 (0.44) | CYP3A4ALDH1A1CYP1A2CRHR1MAOB | |
| SCHEMBL458031 | 0.74 | KMT2A (0.48) | POLBL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL15121085 | 0.73 | ALDH1A1 (0.33) | POLBL3MBTL1MEN1KMT2ACYP3A4 | |
| SCHEMBL1203850 | 0.71 | ALDH1A1 (0.53) | POLBL3MBTL1MAOAMAPTCYP3A4 | |
| SCHEMBL459993 | 0.71 | MAOB (0.38) | POLBMAOAMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103189383-B | Biaryl diphosphine ligand, its intermediate and the purposes in asymmetry catalysis thereof | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2016-11-30 | — | — | CN | disclosed |
| US-9062085-B2 | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-9062085-B2 | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-9062085-B2 | Biaryl diphosphine ligands, intermediates of the same and their use in asymmetric catalysis | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2015-06-23 | — | — | US | disclosed |
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2013-07-18 | — | — | US | disclosed |
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2013-07-18 | — | — | US | disclosed |
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2013-07-18 | — | — | US | disclosed |
| EP-2614069-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | Kanata Chemical Technologies Inc. (CA) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012031358-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184479-A1 | BIARYL DIPHOSPHINE LIGANDS, INTERMEDIATES OF THE SAME AND THEIR USE IN ASYMMETRIC CATALYSIS | AGPS, COASY, BLVRB | POLB 99/4885L3MBTL1 3884/4885MAOA 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.