Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.64 |
| ▸ | ME3 | Q16798 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119432 | 0.85 | HPGDS (0.55) | HPGDSME3SIGMAR1HTR1ADRD2 | |
| SCHEMBL457638 | 0.80 | HPGDS (0.50) | HPGDSL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL15070464 | 0.80 | HPGDS (0.55) | HPGDSL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL14119466 | 0.80 | HPGDS (0.71) | HPGDS | |
| SCHEMBL14119859 | 0.79 | HPGDS (0.60) | HPGDSSIGMAR1DRD2L3MBTL1 | |
| SCHEMBL14119653 | 0.78 | HPGDS (0.69) | HPGDS | |
| SCHEMBL460420 | 0.76 | HPGDS (0.58) | HPGDS | |
| SCHEMBL14119996 | 0.74 | HPGDS (0.72) | HPGDS | |
| SCHEMBL14119801 | 0.73 | HPGDS (0.52) | HPGDSSIGMAR1L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL27557817 | 0.72 | ITGB3 (0.51) | ME3SIGMAR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012033069-A1 | PROSTAGLANDIN D SYNTHASE INHIBITORY PIPERIDINE COMPOUNDS | 大鵬薬品工業株式会社 (JP) | 2012-03-15 | — | — | WO | disclosed |