SCHEMBL4597811

SCHEMBL4597811

CCOC(=O)c1ccccc1C(=O)OC1CCCCC1

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.64
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 5/20 0.50
KMT2A Q03164 4/20 0.48
MEN1 O00255 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
CDC25B P30305 1/20 0.48
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6405726 0.88 ALDH1A1 (0.66) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL8607117 0.87 MEN1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL29372521 0.87 MEN1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL10707097 0.87 MEN1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL29302 0.87 MEN1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL19668120 0.87 MEN1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL31069910 0.87 MEN1 (0.57) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL271491 0.86 TSHR (0.68) TSHRALDH1A1HSD17B10TDP1KMT2A
SCHEMBL31020921 0.86 TSHR (0.68) TSHRALDH1A1HSD17B10TDP1KMT2A
Dibutyl Phthalate SCHEMBL28523512 0.86 TSHR (0.68) TSHRALDH1A1HSD17B10TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146153-B1 AN ANTIPERSPIRANT COMPOSITION UNILEVER IP HOLDINGS B V (NL) 2023-11-01 EP disclosed
US-20230127509-A1 An Antiperspirant Composition CONOPCO, INC., D/B/A UNILEVER (US) 2023-04-27 US disclosed
US-20230124656-A1 An Antiperspirant Composition CONOPCO, INC., D/B/A UNILEVER (US) 2023-04-20 US disclosed
EP-4146152-A1 AN ANTIPERSPIRANT COMPOSITION Unilever IP Holdings B.V. (NL) 2023-03-15 EP disclosed
EP-4146153-A1 AN ANTIPERSPIRANT COMPOSITION Unilever IP Holdings B.V. (NL) 2023-03-15 EP disclosed
WO-2021224133-A1 AN ANTIPERSPIRANT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2021-11-11 WO disclosed
WO-2021224167-A1 AN ANTIPERSPIRANT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2021-11-11 WO disclosed
CN-101188948-A Lignan-containing compositions ARCHER DANIELS MIDLAND CO (US) 2008-05-28 CN disclosed
EP-1897559-A1 Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations Cydex Inc. (US) 2008-03-12 EP disclosed
EP-1897560-A1 Sulfoalkyl ether cyclodextrin based controlled release solid pharmaceutical formulations Cydex Inc. (US) 2008-03-12 EP disclosed
US-4429066-A AUTOMOBILES AND TRUCKS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-01-31 US disclosed
US-4416941-A AUTOMOTIVE PAINTS E. I. DU PONT DE NEMOURS & CO. (US) 1983-11-22 US disclosed
US-4411951-A ACRYLIC ESTER RESIN CROSS LINKED WITH MELAMINE-FORMALDEHYDE RESIN BONDER E. I. DU PONT DE NEMOURS & CO. (US) 1983-10-25 US disclosed
US-4404248-A AUTOMOBILES; TRUCKS; AIRCRAFT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-09-13 US disclosed
US-4396680-A Substrate coated with crater resistant acrylic enamel E. I. DU PONT DE NEMOURS AND CO. (US) 1983-08-02 US disclosed
US-4371657-A AMINO RESIN CROSSLINKING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US disclosed
US-4330458-A High solids coating composition of a blend of a low molecular weight acrylic polymer and a medium molecular weight acrylic polymer and an alkylated melamine cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-05-18 US disclosed
US-4276212-A ACRYLIC ESTER COPOLYMER INCLUDING A HYDROXYALKYL ACRYLATE AND CHAIN TRANSFER AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-30 US disclosed
EP-0029598-A1 An improved high solids coating composition of a low molecular weight acrylic polymer and a polyisocyanate cross-linking agent, and a substrate coated therewith E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-03 EP disclosed
EP-0029596-A1 An improved high solids coating composition of a low molecular weight acrylic polymer and a nitrogen resin cross-linking agent, and a substrate coated therewith E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-06-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127509-A1 An Antiperspirant Composition CUTA, POLR1C, PUF60 TSHR 4500/4885ALDH1A1 1386/4885HSD17B10 782/4885
US-20230124656-A1 An Antiperspirant Composition POLR1C, CUTA, PUF60 TSHR 4194/4885ALDH1A1 1819/4885HSD17B10 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.