Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597915 | 0.89 | STS (0.52) | MAPTALDH1A1NPC1MAPK1HTT | |
| SCHEMBL6498471 | 0.88 | KDM4E (0.55) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL22467690 | 0.88 | KDM4E (0.55) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL21074855 | 0.88 | KDM4E (0.55) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL5576460 | 0.82 | GPR119 (0.54) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL3758709 | 0.81 | GPR119 (0.57) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL13991761 | 0.79 | USP30 (0.46) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL6284531 | 0.78 | ALDH1A1 (0.51) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL4916071 | 0.78 | ALDH1A1 (0.47) | GPR119MAPTALDH1A1NPC1MAPK1 | |
| SCHEMBL4916078 | 0.78 | ALDH1A1 (0.47) | GPR119MAPTALDH1A1NPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |