Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597819 | 0.89 | GPR119 (0.53) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL21074855 | 0.87 | KDM4E (0.55) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL6498471 | 0.87 | KDM4E (0.55) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL22467690 | 0.87 | KDM4E (0.55) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5576735 | 0.85 | STS (0.51) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4610832 | 0.84 | STS (0.49) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5780805 | 0.83 | CYP3A4 (0.49) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL5575926 | 0.83 | STS (0.57) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4596528 | 0.82 | ALDH1A1 (0.48) | STSNPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL4608693 | 0.82 | STS (0.53) | STSNPC1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |