Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.57 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576084 | 0.86 | CCR5 (0.54) | CCR5CCR4KCNH2 | |
| SCHEMBL5576089 | 0.86 | CCR5 (0.54) | CCR5CCR4KCNH2 | |
| SCHEMBL4609996 | 0.81 | CCR5 (0.50) | CCR5CCR4KCNH2 | |
| SCHEMBL4610004 | 0.81 | CCR5 (0.50) | CCR5CCR4KCNH2 | |
| SCHEMBL4610033 | 0.78 | CCR5 (0.43) | CCR5CCR4KCNH2 | |
| SCHEMBL5572449 | 0.78 | CCR5 (0.47) | CCR5CCR4KCNH2 | |
| SCHEMBL4610206 | 0.78 | CCR5 (0.54) | CCR5 | |
| SCHEMBL4608051 | 0.77 | CCR5 (0.46) | CCR5CCR4KCNH2 | |
| SCHEMBL4598523 | 0.77 | CCR5 (0.60) | CCR5CCR4KCNH2 | |
| SCHEMBL4597898 | 0.75 | CCR5 (0.56) | CCR5CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |