Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294913 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HSD17B10LMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4329941 | 0.81 | ALDH1A1 (0.45) | ALDH1A1LMNAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4597214 | 0.80 | TSHR (0.45) | HSD17B10KMT2ACA1CA2TSHR | |
| SCHEMBL27244976 | 0.78 | POLB (0.54) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL5623571 | 0.78 | POLB (0.54) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL3290293 | 0.78 | HPGD (0.50) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL99348 | 0.74 | GABRA1 (0.73) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL921042 | 0.74 | ALDH1A1 (0.59) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL30345339 | 0.74 | GABRA1 (0.73) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL28581525 | 0.74 | HPGD (0.50) | HPGDALDH1A1KDM4EHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |