Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035096 | 0.84 | CXCL8 (0.46) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL490576 | 0.82 | PTGS2 (0.47) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL362699 | 0.82 | PTGS2 (0.48) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL15641407 | 0.82 | PTGS2 (0.48) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL30717242 | 0.82 | PTGS2 (0.48) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL28581525 | 0.81 | HPGD (0.50) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL11125757 | 0.81 | CXCL8 (0.40) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL9402250 | 0.80 | PTGS2 (0.47) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL286787 | 0.79 | CXCL8 (0.43) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL6248977 | 0.79 | MMP2 (0.48) | HPGDALDH1A1KDM4EHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700522-B2 | α-Oxygenated or α-thiolated carboxylic acid phenethylamide derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-20050038082-A1 | Novel $g(a)-oxygenated or $g(a)-thiolated carboxylic acid phenethylamide derivatives | SYNGENTA CROP PROTECTION, INC. | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038082-A1 | Novel $g(a)-oxygenated or $g(a)-thiolated carboxylic acid phenethylamide derivatives | CBR3, CBR1, GLRA1 | HPGD 1516/4885ALDH1A1 482/4885KDM4E 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.