Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830804 | 0.87 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL29565421 | 0.82 | MAPT (0.43) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL4598178 | 0.82 | MAPT (0.43) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL4597629 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL29565457 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDALOX15KDM4E | |
| SCHEMBL4597787 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1HSD17B10HPGDKDM4ETP53 | |
| SCHEMBL30094410 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1HSD17B10HPGDKDM4ETP53 | |
| SCHEMBL4596761 | 0.80 | MEN1 (0.40) | ALDH1A1HSD17B10HPGDKDM4ETP53 | |
| SCHEMBL17929235 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10HPGDALOX15DGAT1 | |
| SCHEMBL4597892 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HPGDKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877856-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | Bausch & Lomb Incorporated (US) | 2008-01-16 | — | — | EP | claimed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | claimed |
| WO-2006119328-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2006-11-09 | — | — | WO | claimed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | claimed |
| EP-1877856-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | Bausch & Lomb Incorporated (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| WO-2006119328-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | disclosed |