Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597629 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29565457 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4597787 | 0.86 | SMN1; SMN2 (0.48) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30094410 | 0.86 | SMN1; SMN2 (0.48) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23169694 | 0.85 | MEN1 (0.36) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23169688 | 0.85 | MEN1 (0.36) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4598124 | 0.80 | ALDH1A1 (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7001887 | 0.80 | EGFR (0.41) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7501698 | 0.78 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL5646123 | 0.78 | MAP3K5 (0.41) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877856-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | Bausch & Lomb Incorporated (US) | 2008-01-16 | — | — | EP | claimed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | claimed |
| WO-2006119328-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2006-11-09 | — | — | WO | claimed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | claimed |
| EP-1877856-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | Bausch & Lomb Incorporated (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070159594-A9 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2007-07-12 | — | — | US | disclosed |
| WO-2006119328-A1 | PHOTOCHROMIC BLUE LIGHT FILTERING MATERIALS AND OPHTHALMIC DEVICES | BAUSCH & LOMB INCORPORATED (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20050254003-A1 | Photochromic blue light filtering materials and ophthalmic devices | BAUSCH & LOMB INCORPORATED | 2005-11-17 | — | — | US | disclosed |
| US-6353102-B1 | FOR OPHTHALMIC LENSES OR CONTACT LENSES | PPG INDUSTRIES OHIO, INC. | 2002-03-05 | — | — | US | disclosed |